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A+ (a positive) blood type & platelet donations
Published by: wktd 2010-03-16
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  • The American Red Cross informed me that A+ blood is especially suited to and needed for platelet donations. I have now read this in several places (see, e.g., http://www.bbsbrc.org/donation_types.htm). Why is it, exactly, that A+ blood is more needed and/or better suited to plateletpheresis than other blood types (except, perhaps, for AB)?


  • Hi mikunifan, Blood banking is one of the most complicated things to understand, after quantum physics! A positive (Called simply ?A pos? in the hospital) blood is not better suited for plateletpheresis than other group and type blood. It?s simply the most common type after O pos! This got me thinking however, as I did some blood banking years ago, so I called the very busy blood bank at Mayo Clinic, Rochester, Minnesota. One of the knowledgeable blood bankers there told me there is no reason that A pos blood is better suited for plateletpheresis and wondered why this was stated on the Red Cross site. Actually, the Red Cross site you cited states: ?Donors with A+ blood are especially needed to donate platelets.? Certainly this is because of need, and not suitability of pheresis. Neither myself nor the Mayo blood bankers could come up with a reason for the Red Cross statement. Looking at the compatibility chart on the following site, you can easily see that people with AB pos blood can receive blood/platelets of any group and type! However, there are fewer people with this group and type. A pos is the second most common group and type, yet can receive only Apos or neg, and O pos or neg. Folks with O ps can receive O pos or O neg blood/platelets. http://www.utahblood.org/facts/abosystem.htm While blood groups, such as A, B, AB, and O are commonly called blood types, but the correct name is ?Group? . Blood type technically refers the Rh factor, negative or positive. For example, A neg (A-) blood is correctly called ?Group A, type Rh negative? Most hospitals transfuse group specific platelets to patients, in other words, A pos platelets to an A pos patient. If group specific is unavailable, another group is used, following a compatibility chart. The amount of red blood cells present in a unit of platelets is usually insufficient to cause a transfusion reaction. Giving Rh positive platelets CAN cause antibodies to be produced in an Rh negative person though. This is only important in women through their childbearing years, and not at all in men or post-menopausal women. http://www.psbc.org/medical/transfusion/scenarios/scenario_02/_frm/frm_17_compatibility.htm http://www.cbbsweb.org/enf/plttx_aboincompat.html More interesting blood banking information: AABB is the best source of information on group and type questions. All hospital blood banks follow AABB standards. http://www.aabb.org/ http://www.mayoclinic.org/donateblood/know.html http://www.utahblood.org/facts/platelets.htm http://www.bloodbankofalaska.org/donating/apheresis.html http://www.newenglandblood.org/medical/type.htm If you have any further questions, please request an Answer Clarification, before rating, and I will respond as soon as possible. Regards, crabcakes





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